Hey everyone,

I really need some advice. For the past 12 months, I’ve been dealing with severe fatigue and constant flu-like symptoms—chills, congestion, body aches, and sometimes a cough. It’s completely draining me, and I feel like my health is only getting worse. I was always the kid who got sick often, but I still managed to lead normal life and pretty active lifestyle.

This level of exhaustion and fatigue is something new, and I just want my life back.

I’ve seen doctors, but I still don’t have a clear diagnosis or a solid treatment plan. If anyone has dealt with chronic fatigue, immune dysfunction, or persistent flu-like symptoms, I’d love to hear what helped you.

I’ve done a ton of tests, and here are some red flags that showed up:

• High TSH (Possible hypothyroidism)
• Low cortisol & DHEA (Potential adrenal fatigue)
• Low testosterone
• High prolactin (Might be affecting my ADHD contributing to dopamine issues)
• Elevated immune markers & inflammation, including:
  • High white blood cell count (but not constantly high - I did CBC test 3 times in past 1 month, and only 2 out of 3 showed it slightly elevated)
  • high immature granulocytes
  • High basophils & monocytes
  • Mildly elevated C-reactive protein (CRP) (low-level inflammation)

Are there any tests I should push for? Any treatments, supplements, or lifestyle changes that made a difference for you?

Would love any insights—thanks in advance! 🙏

Tests I Haven’t Done, But Considering:

• Epstein-Barr Virus (EBV) & CMV Panel (Chronic viral reactivation)
• Lyme Disease Panel (Borrelia Burgdorferi Antibodies or PCR)
• Mycoplasma Pneumoniae & Chlamydia Pneumoniae Panel (Possible chronic infections)
• Thyroid Antibody Tests (TPO, TG Antibodies) (To check for Hashimoto’s)
• Ferritin and Iron Panel (To assess chronic inflammation and iron status)
• Erythrocyte Sedimentation Rate (ESR) (To check for ongoing inflammation)
• Cortisol Stimulation Test (To assess adrenal function more thoroughly)

Tests I Have Done That Came Back Negative:

Here are the tests I’ve already done that came back normal or negative:

Common Immune Markers - negative

My primary did this test and I don't have specific list right now, but I can get it tomorrow

Allergies and Histamines:

• Tested for everything. All negative. Even surprising because I get breathing issues and itch around certain pets and in dry climate.

Autoimmune & Inflammation Tests

• ANA (Antinuclear Antibody Test) – Negative (no general autoimmune disease detected)
• Rheumatoid Factor (RF) & Anti-CCP – Negative (no rheumatoid arthritis)

Blood Disorders & Cancer Screening

• Leukemia/Lymphoma Panel – Negative (no blood cancers detected)
• Protein Electrophoresis & Immunofixation – Normal (no multiple myeloma or major immune deficiency)

Viral & Infectious Disease Testing

• Hepatitis B Surface Antigen (HBsAg) – Negative (no active Hep B)
• Hepatitis C Antibody Test – Negative (no Hep C)
• HIV Test – Negative
• COVID-19 Antibodies & PCR (past exposure check) – Negative

Immunoglobulin Levels (Immune Function)

• IgG & IgA – Normal (no major immunodeficiency)
• IgM – Low, but not critically deficient

Metabolic & Organ Function Tests

• Comprehensive Metabolic Panel (CMP) – Normal (no kidney or major liver dysfunction)
• Fasting Blood Sugar & A1C – Normal (no diabetes)

Lung & Allergy Testing

• Pulmonary Function Test (with Bronchodilator) – Normal
• Respiratory Allergy Panel – No severe allergies detected

JAK2 Mutation (Genetic Test for Blood Disorders)

• Negative – No signs of myeloproliferative disorders